Category Archives: Dr Coimbra

What caused your health issue updated

I’ve updated my Eureka moment article again, now after 5 years of research.

Everybody needs to take responsibility for their own health as we have been constantly misled by modern society and the modern systems. We have come to believe that doctors know everything, often they are are brilliant at what they do but all too often they opt for the prescription pad without considering a natural treatment. Also conventional medicine is based on the one size fits all approach. We are all individuals with different diets and lifestyles surely functional or holistic medicine must be the way forward.

We are all gradually damaging ourselves and conventional medicine is only geared at treating the symptoms and not resolving or preventing the cause . Over 3 years ago doctors were telling me to stop taking the massive doses of vitamin D3 I was taking, I was given several tests but they all came out as normal even the thyroid test despite the fact that I had lost all the hair on the edge of my eye brows a classic sign of a thyroid issue (Thyroid Healthy). I started on a natural thyroid supplement and my eye brows are back to normal. That seems to be the thing now you can carry on going to your doctor and getting a standard often inadequate test or you can do the research yourself. So far I have got far better results treating myself.

Here is why I believe you got your health problem and I got MS.

My conclusions about this are confirmed if you read Death by Modern Medicine: Seeking Safe Solutions: 3rd Edition

If you are overweight that is inflammation that is unhealthy you are damaging yourself, if you have any sort of health condition say Multiple Sclerosis, Parkinson’s, Crones disease, Cancer, Heart issues etc.. that is caused by inflammation. If you keep forgetting things and getting Dementia type symptoms that is inflammation. If you have any health condition diagnosed or not that is probably inflammation.

So what causes inflammation?

Inflammation is caused by the expression of your genes.  Your heath starts at inception where 20% of your health becomes programmed by your genes 80% by your environment. OK that figure has been quoted in a number of publications and I can’t see how that ratio was arrived at, but go along with it as it’s probably close to the truth. Think of your genes being like keys on a giant keyboard and as you live your life your environment plays a tune with your genes switching them on and off, get your environment factors wrong and a bum note is played and the bad genes get the on key pressed. Play that wrong note too often and the keyboard gets out of tune your bad genes get switched maybe permanently on. Its been discovered recently that gene expression can be completely reversed, whereas previously we were all told that some diseases were totally incurable this has been disproved.

My explanation is obviously a very simplistic interpretation but hopefully it gives you the idea. This process to generate a health issue can take years which is why you or your doctors don’t recognise what the cause is, it may have taken anywhere from birth to your current age to form.

So what causes your Genes to be expressed?

Keep on playing the note wrong and the note can’t be pressed anymore it’s damaged it stays on and needs to be re tuned. You have ended up with a issue maybe a disease as your genes have been expressed. Your environment, living\working in a built up area*, your lifestyle, your eating choices, your geographic location, how much sun exposure you have (D3 levels), how much bad air you breath in, insufficient fresh natural air, textiles in your house, some modern materials**,  how much chemical exposure*** you are subject too and how much exercise you get plays the gene keyboard. Stress levels (A massive major player),  plus many many other things…. Basically you cause your own health problems by not providing the optimum environment for your body to thrive and play the correct tune.

*Traffic congestion increases vehicle emissions and degrades ambient air quality, and recent studies have shown excess morbidity and mortality for drivers, commuters and individuals living near major roadways

**Not all synthetic fabrics go straight into the “no” column, but some are more skin-friendly than others. Man-made fabrics—like polyester, nylon, and spandex—and wool may cause skin irritation, known as dermatitis Trusted Source. While most natural fabrics and nylon are breathable, silk and many synthetics are not, and wearing them can lead to athlete’s foot or other irritation or fungi due to trapped moisture. Check clothing tags for anything non-natural and bin it if it causes a rash.

**Asthma is associated with kids being exposed to cleaning products. 

Your body is a finely tuned complex organism designed to be given exactly what it needs to stay healthy and is able to eliminate foods/toxins it doesn’t find optimal for your health  This is why you throw up after ingesting a bad meal. Its also why it stores away food away when it’s not recognised so you build up fat stores. If you eat a health diet  you will naturally not be storing fat, as long as you’re not habitually over eating.

It’s not really that simple!

Unfortunately our modern lifestyles and diet causes amongst other things some of the poor environmental factors. Your body cannot recognise foods that are processed they often have dangerous fats, they are missing vital minerals, or the minerals have been corrupted. Processing extracts minerals from foods or at least changes the constitution of minerals so your body does not recognise them, so your not getting the nutrients your body needs. This all leads to your body storing fat as it thinks your starving its why you can’t shed that weight. Genes will end up getting expressed and you will become ill. It all takes a long time building so you aren’t going to notice the inflammation response building up, that is why you still go on doing the things that are damaging you.

The processed food industry knows all about this yet they do nothing about it except package more processed foods under new ‘healthy’ labels, though it’s still the bad stuff but more attractively packaged you only have to read the labels properly to discover this for yourselves.

But that’s not all, the thing/s that actually controls the whole process is our microbiota. Increasingly, biologists have come to appreciate that microbes make up an important part of our health. Humans are 90% microbes read on…

What set off your immune response?

When I say above that your body cannot recognise processed foods it’s really your microbes that you are confusing. If your Microbes don’t recognise something they may treat it as a threat and try to eliminate it, who knows how your genes will be responding to something that they don’t recognise, they may cause a rash to form, they may cause you to be sick to get rid of what they don’t like, they may cause a serious illness. The reaction will probably be different in each of us we are all unique. So you need to make the right environmental choices mainly but not only with your diet, basically if you want to stay healthy you need to look after your microbiota your own internal community. If you eat a lot of the bad foods you are feeding the bad microbes they will crowd out the good microbes and cause issues. Sugar feeds the bad  microbes.

Maybe they will cause a food sensitivity like Gluten or Wheat intolerance or you already have this sensitivity and don’t realise it, we are not all the same it may manifest itself differently in different people who knows. The first thing to think about is your gut health, if you are not having a bowel movement 2 or 3 times a day you have an issue. You should be having one bowel movement for every big meal you had the day before.

Take control you are the worlds greatest expert on you. Maybe the microbes will cause a child to get acne but maybe in the case of a very young child the lack of the correct microbes will develop into autism – as an aside here the latest research seems to prove this – over use of antibiotics in very young and infants has been proven to cause autism. Tough autism has also been associated with vaccines. If you were born by cesarean section and not breast fed you will be at greater risk, as natural birth ensures the infant inherits the optimum microbes from their mother. If you take broad spectrum antibiotics you will be killing the good as well as the bad microbes you are probably doing just as much bad as good.

Too much sugar will grow your colony of bad microbes you will be feeding the inflammation that will cause elevated blood sugar levels – Diabetes. The added sugar that all processed foods seem to have is dangerous and highly addictive if you can’t get rid of body fat its because your building up the inflammation by eating the wrong diet. With processed food full of sugar each mouthful is feeding the inflammation response in your gut microbes. Sugar is just one factor there are quite a number of potential inflammatory things but we are all different and it’s not always going to be obvious, it could be Gluten or Wheat or Dairy it could be that you live close to roads and a breathing in exhaust fumes it could be that you are a heavy user of cleaning products and are breathing in the fumes, it could be the air freshener that your are breathing in. You could be killing your good bacteria by using anti bacterial products in your home killing microbes so causing your children not to build up any natural immunity to good bacteria so thus getting allergies or asthma it could literally be anything in this modern society. People in the past did not have the modern day diseases that we are all getting. We are causing our own health problems by living in this modern world and we have to start making changes ourselves or we will just be adding another person to the increasing health problem. Stop treating all germs and bacteria as a problem some are really good friends to you.

You need to discover what sets off any immune response in your body by gradually working through your diet and lifestyle and making changes.

What you can do…..

No supermarket meats unless they are organic grass fed, they are damaging as they fast grow animals, sometimes using antibiotics though banned in the UK they can still be in the food chain from muck spreading as fertilizer and the source of the processed foods may be from a country that has less stringent rules on production . Meat if used in your diet should contribute only 5% of your plate. Eat only grass fed meats preferably organic. Know where your meat comes from. A totally natural diet gives the animal the natural balance of omega 3 & 6 fatty acids, so you’ll be taking in the right balance from that part of your diet. Omega fats are a vital but only in the natural balance.

Autism has been seen to be as a result of heavy metals in vaccines start looking at detox products like Advanced TRS, or Pure Body extra strength   You could also look up the work of Dr Jennifer Daniels and the turpentine cure.

No vaccines full stop, do your research they have never been proven to work despite what you’ve been told, it’s been well proven  that giving a child the MMR vaccine at too young an age causes autism. If this has happened to your child see above. The hidden amount of damage from the latest round of COVID vaccines over 24,000 reported deaths so far apparently, look at the VARS database freely available to download.

No processed foods or foods where you can’t clearly understand the ingredients on the label.

No deodorant that has aluminium in the contents. Too much aluminium has been found in the brains of Alzheimer patients. In fact make your own so you know whats in it.

No cooking with Aluminium pans or tin foil.

Introduce more relation time yoga, Pilates, mindfulness, breathing exercises etc…

No toothpastes with fluoride in the contents look up the harm it can do read this is a post.

No antibiotics unless in desperate need and if used followed up by a quality recommended course of pre and pro-biotics. I find a good source of supplements to be Amazon by reading the reviews, as long as there are sufficient reviews to give you an indication of whether it is a quality product, it’s the easiest way to get supplements and probably cheaper than health stores as you can also shop around on price. No binders, fillers or GMO. Preferable natural organic natural source.

No antibacterial cleaning products your killing the good guys. Watch out for cleaning products especially if you find you have a wheat or gluten intolerance as these guys are often in many non food products and listed under different names.

Eliminate stress as much as possible or at least manage it better.

Take quality supplements vitamins and minerals. I find turmeric is a fantastic natural anti-inflammatory only buy organic too many bad brands out there.

Get good quality sleep if you are struggling in this are use quality natural supplements do some research in this area one major reason might be is that you are short on magnesium a major factor for most  people are deficient due to modern farming methods read this book:-

Make an effect to detox on a regular basis. If you have been getting vaccines then start taking some kind of heavy metal detox product. Same as if you have any amalgam fillings you will have mercury exposure which might have caused your issue in the first place. Get rid of your amalgam fillings using a suitably qualified dentist who knows the dangers of mercury.

Lower your alcohol consumption it affects you sleep amongst other things, sleep is one of the most important things for your health.

Stop all our electrical devices in your room for sleep and don’t have them in your room whilst you sleep stop your WiFi connection overnight.

No pharmaceutical products drugs mask symptoms and leech magnesium Your body gives you the symptom to inform you that something is wrong listen too it and research for a natural treatment to support you. Most symptoms will benefit from a high dose vitamin D3 regime.

Vitamin D screening assay is readily available, but the reported lower limit of the normal range. Note the normal range is the range needed not to die so very inappropriate as a measure.

Get your D3 blood level tested and start supplementing if your results show you under the current recommended optimal vitamin D level of  50-70 ng/ml. This amount is totally inadequate for disease prevention. Based on the epidemiological studies, approximately 75% of all adults worldwide have serum 25(OH)D levels of <30 ng/mL.  Though if you are treating cancer or heart disease, you should try to get the level as high as 70-100 ng/ml. If you live in the UK then supplement up to 30,000 IU’s a day for an adult. The D3 supplement will mention don’t go over a much lower amount don’t worry it wont kill you. If you go over 30,000 IU’s add K2 to your supplements to prevent hyper-calcification.

Read the book from Jeff T Bowles about his self experiment with D3 and follow his advice in the book. A D3 blood test is a critical test that your doctor is very probably ignoring. I myself have supplemented 100,000 IU’s a day for a month and then 200,000 IU’s a day for a few days and I’m still around but currently now on 70,000 a day. You could try to follow the Coimbra Protocol.  Dr Coimbra is a Neurologist from Brazil who is reversing MS symptoms he has had a 95% success rate on over 25,000 patients and totally curing Crones disease and other diseases with high dose D3, Unfortunately as I live in the UK we have no doctors following this protocol so I am doing high dose D3 without a doctors guidance. What Dr Coimbra misses is that many people have failures with his protocol due to heavy metal poisoning, if fact heavy metal poisoning may give you the exact same symptoms as having Multiple Sclerosis.

As an aside you could follow the Facebook group Personalized Vitamin D3 For MS With Michael Cawley As he personalises treatment with supplements very successfully.

Watch out for nano particles the are in the food chain now and in vaccines they won’t be on labels as they are unregulated seek out organic or home grow if possible.

No farmed fish products – wild caught Atlantic fish seem to be the least polluted but there is no guarantee so only eat once a week. Farmed fish are fed grains and not being a natural diet it affects the fish in a detrimental way, so it will have a detrimental affect on you.

Watch out if you are taking fish oil supplements our seas our now so polluted look st the evidence to ensure the supplement is free from contaminants.

Eliminate products with added sugar. The latest research on Alzheimer’s labels it as type 3 diabetes so keep on eating and drinking sugary products you know where you’ll be heading.

Always filter tap water researchers found adults with high levels of dichlorophenol – a chemical by-product of chlorine – in their urine, were up to 80 per cent more likely to have a food allergy see

There are a million and one things that can be added to this list but you must make and own food decisions for your own health journey.

Food is not enough now, as our soils are so deficient you will need to supplement. Most important is magnesium, Omega 3, Vitamin C, E, Zinc, Selenium, D3, K2 and the full spectrum of B vitamins make sure B12 is in there, B12 deficiency can lead to dementia like symptoms, and will lead to dementia if not addressed.

There is a great book that looks at our bacteria from birth and what manipulates our development thereafter. It explains in great simplistic detail what’s happening in your microbiota.

Can inflammation be reversed once its manifested into a disease?

Yes definitely but it depends many things can be reversed you only need to look at YouTube you’ll find videos of individuals who have cured themselves from cancer by dietary changes. Dr Terry Wahls reversed many of her Secondary Progressive MS symptoms through the Paleo Diet. I’m reversing my MS symptoms through D3 supplementation and diet changes but then again it depends we are all different and you need to be very disciplined in your approach, but anything is possible and the research is out there if you go looking. Healing is a marathon not a sprint.

Remember there is no such thing as an incurable disease and I believe it is criminal to say a health condition is incurable as the placebo effect has a massive role to play in your health if you think your not going to get better every little worsening change to a symptom will focus your attention on getting worse not better STOP believing in getting worse focus totally on getting better.

Videos of D3 success stories

Video success stories of vitamin D









Dr. Cicero G. Coimbra’s Vitamin D Protocol for Multiple Sclerosis


A Message to Grassroots Health Participants from Dr. Coimbra Video Date: February 28, 2016 Over 4,000 MS patients treated now all in remission. Come on Doctors only 27 doctors around the world following this successful treatment don’t let Big Parma stop you!


MS Treatment Video by Dr. Coimbra – 95 percent of auto-immune cured with vitamin D in high doses – April 2014


English subtitles but well worth reading, If only we could find an enlightened doctor in the UK who would follow this protocol. 2014 article 2.500 patients treated 95% success rate many more now.

Great info on many Facebook groups that can help you if you want to start on D3.

English transcript:-

Clinical interventions have shown that Vitamin D can prevent, treat, and even cure Multiple Sclerosis, at a tiny fraction of the cost of the drugs now used to treat it, and without side effects.

Summary: lack of consensus on how much to prevent, treat, or cure MS

  • How much Vitamin D to prevent many diseases – such as MS
  • How much Vitamin D is needed to treat MS? There is currently no agreement
    The recommendations range from 40 to 100 ng – which can result of a dose ranging from 3,000 to 20,000 IU/day
  • How Vitamin D is needed to Cure MS?: It appears that 20,000-140,000 IU daily may be needed to CURE the disease
    You must be under the supervision of a doctor who knows what to watch for in your individual situation.
    High doses of Vitamin D cannot be used as a monotherapy.
    You will need to adjust the cofactors: Typically increasing Magnesium and Vitamin K2, and reducing Calcium intake.
    Your doctor will monitor these and might increase your intake of Vitamins B2, C, as well as Omega-3

A few highlights of the video by VitaminDWiki

  • Use Physiologic dose, similar to the 10,000 units of being out in the sun for a while
  • Vitamin D modifies the operation of about 4,500 genes
  • Complete control (cure) in 95% of patients with MS and many other auto-immune diseases (TH17)
  • Trying to understand why 5% are only partially helped. Smoking?
  • Dose size is highly patient specific: treatment ranges from 30,000 to >100,000 IU daily
  • They have treated more than 2,500 MS patients
  • They do not know how long to keep the person on high dose vitamin D
  • He has his patients stop all dairy product and drink at least 2.5 liters of water a day
  • He will never do a double-blind, randomized and placebo (clinical trial) using vitamin D – needs to be tuned for each patient
  • He mentions success with a great many other diseases – many are bolded
  • He Believes some diseases are trggered by emotional factors
  • They do not know whether daily, weekly, and monthly doses work equally:they use daily doses to avoid large variability of blood levels
  • Daily doses of vitamin D are increased until PTH reaches the lower normal range.
  • His daughter has taken 10,000 units of vitamin D per day for more than six years.
  • Do not really know of any effect of vitamin D on the normal intestinal flora.
  • Older people have then a lesser amount of vitamin D receptors in every single cell
    (this is a news item for VitaminDWiki – was previously aware of less production in the skin and adsoption in the gut)
  • He typically also gives vitamin B2 to all patients: B2 is needed to process Vitamin D.
    10% of people have genetic problem such that B2 is low, but it is too hard to test for B2 deficiency
  • He recommends 10,000 IU daily for PREVENTION

PTH vs Vitamin D – from the web

See also. if you Understand interview in Aug 2014

auto-translated so there are various errors
Text bolded by VitaminDWiki

  • 0:12 The protocol was created by the following question:
  • 0:16 at a given moment of my professional life,
  • 0:20 I felt very strongly the need to try to help change this idea
  • 0:29 that neurology is a medical specialty made from brilliant diagnostic
  • 0:36 but no effective treatment available for neurological diseases;
  • 0:41 and that is how it is regarded in the medical environment: a specialty of brilliant diagnostic
  • 0:49 but no effective treatment.
  • 0:52 When I finished a period of clinical training in Miami (USA), at the Jackson Memorial Hospital,
  • 1:03 I returned to St. Paul with the aim to specialize
  • 1:06 and to start doing research using laboratory animals
  • 1:12 and creating models of neurological disease in rats, with the aim of testing
  • 1:21 new diagnostic possibilities.
  • 1:23 During the research, you are obliged to have cutting edge knowledge,
  • 1:38 you can not just read a book that has information on neurology of 5 or 10 years ago;
  • 1:46 you are obligated to know what was published last week
  • 1:51 about the research that is being done.
  • 1:57 And that was our goal.
  • 2:02 Having the huge amount of publications that have not been published in textbooks,
  • 2:08 we wondered why this information is not applied in clinical practice;
  • 2:15 information and sometimes they are really simple.
  • 2:18 Little by little, we are convinced that,
  • 2:27 many things which would be a great benefit to patients,
  • 2:33 are not discussed in Congress and medicine are not put in the textbooks,
  • 2:41 simply because they can reduce the consumption of medicines,
  • 2:47 especially when these drugs are expensive.
  • 2:53 At any given time we were convinced that vitamin D
  • 3:02 stimulate the production of several substances neurorigenerative
  • 3:10 in the brains of adults, children, embryos, fetuses. And is extremely important,
  • 3:20 time for development, and for the functions of the nervous system (same thing in the nervous system of an adult).
  • 3:30 These skills are not available on medical books
  • 3:34 and most doctors are not aware of the importance of this hormone,
  • 3:40 that is not a vitamin, is a hormone
  • 3:42 which induces the formation of regenerative substances of the nervous system.
  • 3:47 And we have begun, for this reason
  • 3:50 to administer vitamin D to people who had neurodegenerative diseases
  • 3:56 and we did not care to patients with Parkinson’s
  • 4:03 and we started to make vitamin D in doses physiologically realistic.
  • 4:10 It is important to say that the daily dose is recommended today that, internationally,
  • 4:20 does not exclude any patient from vitamin D deficiency,
  • 4:27 is a negligible dose, well below the physiological dose.
  • 4:32 And then, when we started to give the physiologic dose, which is the dose of 10,000 units per day,
  • 4:39 ie the dose that is produced with a few minutes of exposure to the sun, namely,
  • 4:44 if you’re wearing an undershirt and shorts, his legs and arms exposed to the sun,
  • 4:53 will produce in 20 minutes, if you have light skin and if you are young, 10,000 units of vitamin D per day.
  • 5:04 Then, 10,000 is a physiologic dose, is not a super dose.
  • 5:08 However, most doctors consider this potentially toxic dose.
  • 5:16 And these doctors today say that the recommended dose is 600 International Units.
  • 5:32 So, the recommended 600 IU,
  • 5:34 but if a person is exposed to the sun for 20 minutes, producing 10,000 units!
  • 5:43 Then, there is an obvious difference between the medical practice and scientific knowledge.
  • 5:51 Then, we begin to give 10,000 people with neurodegenerative diseases,
  • 5:57 and I remember a patient with Parkinson’s, which received 10,000 of vitamin D,
  • 6:05 when he returned for the second visit, after 3 months (taking 10,000 IU of vitamin D per day)
  • 6:13 had a lesion of vitiligo on the face
  • 6:19 had declined so much that in a few months of administration of 10,000 IU.
  • 6:32 This led us to search for information in the medical literature
  • 6:37 in relation to the effects of vitamin D in the immune system.
  • 6:41 We were surprised by the huge amount of publications that were already available in 2001-2002.
  • 6:57 Based on this first result, we have begun to 10,000 units of vitamin D to patients
  • 7:04 with multiple sclerosis, which is the most common autoimmune disease in neurology
  • 7:11 and the one that has the most devastating effects of neurological patients.
  • 7:17 We were surprised to see how these patients are improved.
  • 7:23 And this was the starting point, in attributing a high value on vitamin D
  • 7:35 in the treatment of autoimmune diseases.
  • 7:37 Today we are absolutely convinced, along with the scientific community that deals
  • 7:48 Research on vitamin D, which studies the effects of vitamin D in the immune system:
  • 7:54 Vitamin D is the major regulator of the immune system
  • 8:03 and modifies the operation of approximately 4,500 genes
  • 8:12 in every cell of the immune system. It is a substance without equal.
  • 8:21 I do a comparison
  • 8:23 to explain what I mean with 4,500 genes that are regulated in their activity by vitamin D.
  • 8:36 Imagine a skyscraper where there are many commercial cinemas. Imagine that
  • 8:45 4,500 doors in this building can be opened or closed by a unique key.
  • 8:55 Then you have to compare the skyscraper with each of the cells of the immune system
  • 9:02 and the key is vitamin D.
  • 9:05 When you lack vitamin D, the patient fails to regulate, ie open or close,
  • 9:13 stimulate or reduce the activity of 4,500 biological functions within the cells of the immune system.
  • 9:23 The lack of this substance is a disaster for the immune system!
  • 9:37 The elements that make up the treatment, in reality are summed into a single element, which is vitamin D.
  • 9:48 People who have autoimmune diseases, according to what has been published in the scientific literature
  • 9:58 inherent in this argument, these people have a partial resistance to the effects of vitamin D;
  • 10:08 and this is genetically inherited from the father, mother or both.
  • 10:15 This resistance concerns the effects of immuno-modulators of vitamin D, and is a resistance partial and not complete.
  • 10:24 And this is the reason for which these people are subject to developing autoimmune diseases.
  • 10:31 Then the great element, perhaps the only (maybe the others are responsible for 5% of the results)
  • 10:42 but 95% of the results that we have obtained in the control of autoimmune diseases,
  • 10:48 in particular in the control of multiple sclerosis, the effects are due, at 95%, to vitamin D.
  • 11:03 And we need to give very high doses of vitamin D to get complete control of the disease.
  • 11:12 These doses are not equal for all patients, are specific for each patient
  • 11:24 and are adjusted according to the degree of resistance that every person with an autoimmune disease
  • 11:33 has for vitamin D (to the degree of resistance that possesses in relation to the effects of vitamin D).
  • 11:41 What we have done is to develop a method to adjust the daily dose for each individual patient,
  • 11:51 and it is done through laboratory tests.
  • 11:55 You collect laboratory tests before treatment,
  • 12:00 after which damage of the doses already established vitamin D; and after at least 2 months,
  • 12:09 which is the time required to increase and stabilize the level of vitamin D in the blood of patients.
  • 12:19 After 2 months refer these tests and comparing the results obtained before and after treatment.
  • 12:31 Through this comparison, we can adjust the individual dose for a given patient.
  • 12:38 And after two months we adjusted, we get
  • 12:44 the full effect, which means, in practice, to obtain the status of a suppression of activity of the disease.
  • 12:55 The disease remains suppressed after 2 months after dose adjustment.
  • 13:09 Therefore, we are currently working with 5 doctors who help us here at the clinic. Personally, I have already visited about 1,300 patients.
  • 13:28 In the clinic, counting the doctors working with us for about 1 year, 1 year and a half, a total of 2,500 patients were visited
  • 13:42 and we are also training doctors working abroad.
  • 13:49 There is one in Argentina, which already works with our protocol, as well as in various cities of Brazil.
  • 13:58 These doctors are visiting hundreds of patients each.
  • 14:04 So I can tell you that we here at the clinic approximately 2,500 holders of multiple sclerosis,
  • 14:14 we’re just talking about this disease. If we speak also of other autoimmune diseases, certainly
  • 14:25 we have moved to 3000 patients, but speaking only of multiple sclerosis, are 2,500 patients.
  • 14:34 This number may still be much greater,
  • 14:36 considered that do not charge those patients who were visited
  • 14:40 10 or 12 doctors working in other capitals of Brazil
  • 14:46 after the treatment here.
  • 14:48 Everyone must have visited more than a hundred patients,
  • 14:55 then surely this number has reached thousands of patients seen
  • 15:00 and also we are receiving patients from abroad in various countries.
  • 15:05 This is a phenomenon of the Internet, nowadays, people create groups
  • 15:12 and this in a sense is good, because patients come into contact with each other,
  • 15:23 to share experiences they have had with the different treatments.
  • 15:31 And this has created a phenomenon propro of our day.
  • 15:34 Today, the vast majority of patients we look after having had access to the internet.
  • 15:43 We have a patient that you have also interviewed, his name is Daniel Cunha, who was a journalist
  • 15:50 who has reached the turning point (“high”) in our clinic, is a former bearer of multiple sclerosis, this is an important thing that you say.
  • 15:59 Because after that we can adjust to treatment, ie, the dose of the patient
  • 16:05 and prove that in two consecutive spaced resonances of 1 year, ie, separated by 1-year interval,
  • 16:18 there has been no appearance of new lesions, recent lesions can disappear, but there is no activity in the lesion,
  • 16:29 then when we are able to prove this and the patient has improved,
  • 16:36 if he did not damage the oldest, back to having a normal life,
  • 16:41 at the end of the two years of treatment, during which we do 3 or 4 visits,
  • 16:55 at the end of this period of two years of treatment, the patient reaches the “turning point”
  • 16:59 you have to keep the dose of vitamin D with the necessary precautions to avoid causing intoxication,
  • 17:09 but you have to keep the dose of vitamin D and recommend that the patient come back two years later for a re-evaluation,
  • 17:15 Then, after five years for a new revaluation.
  • 17:19 We do not know yet how long the patient needs to maintain this high dose of vitamin D
  • 17:26 and now the treatment is for an indefinite period, demanding that patients do this revaluation
  • 17:34 after two and five years, and maybe this time we will be able to establish
  • 17:42 a criterion to determine if they can lower the dose and which of them should be pursued,
  • 17:50 but at this time the treatment is maintained for an indefinite period.

Video starts playing here normally. You can rewind it to see the entire video

  • 18:01 Approximately 95% of patients with multiple sclerosis, the disease remains in remission permanently.
  • 18:13 While they maintain this high dose, the disease remains inactive,
  • 18:24 without signals, neither clinical nor laboratory of new lesions.
  • 18:30 5% of patients achieved a partial result just means that they get improvements,
  • 18:42 but do not have the complete remission of disease activity.
  • 18:49 We, at this moment, we are studying what are the reasons that lead to this 5% not reach
  • 19:01 complete remission of multiple sclerosis and arrived at two fundamental factors:
  • 19:10 the biggest of these is the maintenance of a high emotional stress, very high.
  • 19:20 We know today that emotional stress can seriously undermine the result of this treatment.
  • 19:28 The other factor that can affect the outcome of this treatment is the habit of smoking:
  • 19:35 smoking affect much the result of treatment with vitamin D,
  • 19:44 but this is not a factor to be related specifically to vitamin D,
  • 19:49 There is no information in the medical literature that say that the habit of smoking accelerates the progression of multiple sclerosis,
  • 19:58 even if the patient is under the traditional treatment.
  • 20:02 When I say 95%, are those patients who are not some other type of treatment, if not the high dose of vitamin D,
  • 20:16 associated with a diet and hydration abundant, that are necessary to avoid the side effects.
  • 20:25 Apart from this, it may be that the infection continued, as the urinary tract infection,
  • 20:35 in patients before starting this treatment already suffering from a series
  • 20:41 problems of the function of the bladder, urinary function,
  • 20:48 who develop urinary tract infections easily continuous
  • 20:54 we also know that these continual urinary tract infections may reduce the immunomodulatory effects of vitamin D.
  • 21:05 I speak of immunomodulatory effects, because vitamin D does not suppress the activity of the immune system.
  • 21:15 Today, we know, for established knowledge, that vitamin D suppresses specifically the type of immunological reaction,
  • 21:28 not physiological, aberrant, which is known by the acronym “TH17”
  • 21:38 which is the immunological reaction that causes autoimmune diseases.
  • 21:45 So, all autoimmune diseases, the immune system throughout the aggression against his own body
  • 21:53 are caused by a type of reaction that is not normal, it is not physiological, is abberante and is called “TH17”.
  • 22:01 Vitamin D is the only substance, at least to my knowledge,
  • 22:07 which is capable of selectively inhibit this reaction, without prejudice to the other reactions of the immune system.
  • 22:15 Indeed, vitamin D enhances the ability of the immune system to react against viruses, against bacteria, such as the bacillus of tuberculosis.
  • 22:28 The ability of our immune system to react against these microorganisms
  • 22:35 is enhanced by the administration of vitamin D.
  • 22:41 It is already established knowledge in the scientific community that carriers of tuberculosis need
  • 22:55 to be supplemented with vitamin D, so that the effects antituberculosis become more effective.
  • 23:03 Furthermore, it is known that the patients, for example, carriers of HIV or hepatitis C carriers, they need to be integrated
  • 23:14 with effective doses, and not the daily doses internationally “recommended”
  • 23:22 but a physiological dose of 10,000 units per day, so that the hepatitis C virus does not cause too much damage to the liver,
  • 23:36 as would happen if there was a deficiency of vitamin D.
  • 23:40 The same goes for the other examples of HIV and tuberculosis.
  • 23:54 Yes, Crohn’s disease, inflammatory bowel disease, including ulcerative colitis
  • 24:04 are diseases of which we are able to have __complete control, using the same treatment protocol._-
  • 24:17 It ‘ his important question, because the use of vitamin D in the treatment of autoimmune diseases
  • 24:26 is not directed to a disease or another, but it is directed at the regulation of the immune system. For example:
  • 24:37 under the effect of vitamin D, the immune system increases the amount of a type of cell
  • 24:48 that are produced by the immune system with the aim to keep adjusted.
  • 24:53 These are called “regulatory T cells” and the amount of these cells increases very much under the effect of vitamin D.
  • 25:04 Simultaneously, the reaction TH17, which is an abnormal reaction, not physiological,
  • 25:12 aberrant, is selectively inhibited by vitamin D.
  • 25:16 These 2 things are very important for the control of any autoimmune disease.
  • 25:23 These autoimmune diseases that you mentioned such as inflammatory bowel disease, Crohn’s disease and ulcerative colitis,
  • 25:35 are cases that we have dealt with and responded in complete form.
  • 25:44 The patient lives completely free from manifestations of the disease and maintain a normal life,
  • 25:50 but we must also continue the diet I mentioned before. It can not ingest dairy products,
  • 25:58 no food or wholly made from milk and must also maintain hydration of at least 2.5 liters of water per day.
  • 26:12 Again, autoimmune diseases you mentioned, so far all the cases,
  • 26:19 which are not so many as the cases of multiple sclerosis, but are still dozens of cases,
  • 26:26 all responded in full, without suffering the effects of vitamin D in high doses.
  • 26:42 This question, in relation to the double-blind studies, it is very important because you can not randomize metabolic errors.
  • 27:00 What I mean is that if there is a person who has a metabolic problem diagnosed by laboratory
  • 27:09 for example, a person with hypothyroidism (low thyroid hormone),
  • 27:16 which is potentially lethal and can cause damage to the health of the person, if it is not corrected.
  • 27:27 Another example is the type 1 diabetes in children who do not produce insulin,
  • 27:37 I am obliged to correct this deficiency and have to administer insulin.
  • 27:45 So, in these circumstances, when the patient has a metabolic problem, a deficiency,
  • 27:51 acquired resistance in hereditary form, in relation to a hormone or a vitamin, I am obliged to correct.
  • 28:05 If I do not correct it, I make a mistake of medical negligence.
  • 28:09 Then, when you’re talking about a double-ciecorandomizzato, you’re telling me
  • 28:15 that I have to have a group of patients who will be treated, for example, with high doses of vitamin D
  • 28:24 and a group of patients who receive a placebo;
  • 28:28 and doctors and patients involved in this study are not aware
  • 28:33 of which patients receiving vitamin D and which patients receiving the placebo.
  • 28:40 Very well, I could not do these studies to children with diabetes, for example.
  • 28:48 We’ve never done a double-blind randomized to know
  • 28:55 if the insulin is suitable for children with diabetes. Never did and never will.
  • 29:00 The same thing happens with people who have hypothyroidism, because we are obliged to give a cure.
  • 29:08 You will not ever done a double-blind, randomized, where a group will receive thyroid hormone and the other a placebo.
  • 29:17 The same thing happens to the deficiency of vitamin D.
  • 29:21 A deficiency of vitamin B12 can cause a devastating neurological disorder that destroys the spinal cord,
  • 29:30 so you can not leave a person with vitamin B12 deficiency, without treatment, because I would be remiss.
  • 29:41 You can not leave a person with pellagra, which has a deficiency of niacin (vitamin B3), because it can cause diarrhea,
  • 29:59 dermatitis and even death. So, these people can not be left with a deficiency.
  • 30:11 If I do a double-blind, randomized, I’ll be careless with 50% of patients.
  • 30:20 The placebo group will be the victim of medical malpractice.
  • 30:25 This is a very important concept,
  • 30:28 because today we try to tell the class that any result published in the medical literature
  • 30:36 should not be considered if it was not the result of a double-ciecorandomizzato.
  • 30:42 This is a big mistake.
  • 30:45 People with vitamin D deficiency or resistance to the biological effects of vitamin D,
  • 30:53 for them this deficiency must be corrected and this resistance must be compensated with higher doses,
  • 31:01 which are able to restore in this individual all the biological effects of vitamin D.
  • 31:07 So, there are no double-blind study ciecorandomizzato and we will not do with any patient,
  • 31:15 because there are two main basic principles of medical practice, which is taught in all schools in the Western world.
  • 31:32 The first principle is not to worsen the situation, not hurt,
  • 31:41 not to act on your patient in a worse shape than his clinical situation.
  • 31:49 And the second principle is that the patient should receive all possible benefits.
  • 31:58 So, if I left a patient with vitamin D deficiency,
  • 32:03 knowing that vitamin D is a great immunomodulator, perhaps the most potent immunomodulatory substance that exists in nature,
  • 32:16 a patient who has an autoimmune disease and the immune system has not adjusted
  • 32:23 and produces an immunological reaction aberrant, non-physiological, called TH17,
  • 32:31 if I leave this patient with a deficiency of the unique substance that selectively, in a powerful form,
  • 32:37 is able to inhibit this reaction TH17, producing regulatory lymphocytes, I’ll be negligent towards this person.
  • 32:47 SoI will never do a double-blind, randomized and placebo using vitamin D
  • 32:57 in people who have autoimmune diseases. Why? Why not do these things with my daughter,
  • 33:02 with my wife and even with my patients.
  • 33:13 We have started to use vitamin D in the treatment of autoimmune diseases in the interest of the patient.
  • 33:21 Our goal was not looking, was not to convince anyone,
  • 33:27 but was simply fulfill the 2nd basic principle of medical practice:
  • 33:32 optimally benefit the patient
  • 33:37 ie, if the patient has a deficiency of a potent immunoregulatory known and documented,
  • 33:43 we need to correct this deficiency,
  • 33:45 if it has a resistance, we need to increase the dose so that it can compensate for this deficiency.
  • 33:54 Then, we have accumulated a lot of data over this period and we have gained experience in adjusting the dose for these patients.
  • 34:08 We have published preliminary data on vitiligo and psoriasis, and were the only diseases where we were able
  • 34:25 being approved by the ethics committee of the medical-Unifesp (our university) research.
  • 34:32 We wanted it to be implemented on other diseases, but unfortunately there are factors that many times we do not understand,
  • 34:42 because they are negative with respect to the willingness to do a treatment that could bring benefits,
  • 34:51 as we do not understand how you can deny the ethical conditions so that it is correct a deficiency in a patient.
  • 35:03 I can not understand, but the answer was negative for certain diseases.
  • 35:07 This did not stop us to continue to treat our patients according to their interests
  • 35:14 and we have accumulated a wealth of experience in the cases very well documented.
  • 35:20 And when we would have the opportunity, we will ask an ethics committee that would allow us to evaluate retrospectively these cases,
  • 35:33 if this will be possible. Why we have rules for scientific publications.
  • 35:42 Then, when it will submit a publication to a magazine where there are 2,500 patients treated with high doses of vitamin D,
  • 35:57 and want to publish the outcome of the cases, the publisher of the magazine will ask where is the approval of the Ethics Committee,
  • 36:04 because otherwise we can not send our experience.
  • 36:10 So, first we need to urge the Ethics Committee,
  • 36:16 to approve in a review of the medical records of these patients.
  • 36:21 With the review of the medical records we can send the material to the medical journal. Hopefully there are no problems
  • 36:31 with regard to the retrospective review of the clinical history of the patients in the 11 years of monitoring.
  • 36:39 But I do not know why sometimes some people make decisions not appropriate
  • 36:58 with regard to the dissemination of knowledge and for the benefit of patients.
  • 37:11 Yes, exactly, the success rate is similar to multiple sclerosis.
  • 37:18 But it is important that it be said that when we published this work for psoriasis and vitiligo,
  • 37:24 we used a fixed dose for all patients of 35,000 units per day,
  • 37:31 associated with a dairy-free diet to avoid the toxic effects to the kidneys, and plenty of hydration.
  • 37:40 At that time we did not use this method of adjustment of the dose for each individual patient.
  • 37:48 We achieved these results by 95% of patients, when we used this method
  • 37:57 Individual adjustment of the dose for each patient,
  • 38:00 taking into account the response of the laboratory that each patient shows
  • 38:06 through the comparison of laboratory tests, made before and after treatment, ie after 2 months.
  • 38:18 Then the result, in other words, is passed to the 95% success,
  • 38:26 when we started using this method of adjustment
  • 38:32 on the response of laboratory tests for individual
  • 38:34 that each patient according to a predetermined dose common.
  • 38:47 Then, high doses of vitamin D work for autoimmune diseases in general.
  • 38:54 Autoimmune neurological diseases where we used the vitamin D,
  • 38:59 In addition to multiple sclerosis, are: the isolated optic neuritis,
  • 39:09 Guillain-Barré syndrome (GBS), polyneuropathy of autoimmune origin,
  • 39:26 myasthenia gravis. These are the neurological disease of autoimmune origin that I remember at this time.
  • 39:42 The result of this treatment, when we use the method of adjustment of the individual doses
  • 39:50 for each patient was the same as in multiple sclerosis: 95% of total suppression of autoimmunity.
  • 39:59 This does not mean that the older irreversible damage caused by the immune system,
  • 40:06 considered as pre-existing damage, regress.
  • 40:12 In general, we obtain as a result a complete or almost complete regression, of the lesions
  • 40:20 that were formed in the period of 1 year prior to initiation of treatment with high doses of vitamin D.
  • 40:36 There are other diseases, whose appearance is favored or employee is
  • 40:42 by the presence of a deficiency of vitamin D.
  • 40:45 For example, the recurrence of abortions in the first trimester of gestation.
  • 40:53 To date, this is considered an autoimmune disease.
  • 40:56 The immune system rejects the implantation of the embryo.
  • 41:00 This event is dependent on the presence of vitamin D deficiency
  • 41:06 and a partial resistance to the biological effects of vitamin D. immunoregulatory
  • 41:11 The presence of hypertension, high blood pressure or high at the end of pregnancy,
  • 41:19 situations in the so-called “pre-eclampsia or eclampsia,” putting at risk the life of the mother in late pregnancy,
  • 41:29 that the obstetrician must anticipate the birth by cesarean.
  • 41:39 All this can be prevented by administration of adequate doses of vitamin D.
  • 41:49 For proper dosages mean 10,000 units per day.
  • 41:54 In addition, pregnant women who do not expose themselves to the sun in an appropriate manner,
  • 41:59 thus favoring very low levels of vitamin D, they run a high risk of giving birth
  • 42:06 children who can then develop a problem of autism.
  • 42:11 Autism is highly favored by the deficiency of vitamin D during pregnancy and in the first years of life.
  • 42:20 The vitamin D deficiency, occurring early in the life of an individual during the end of gestation
  • 42:26 or in the first years of life, greatly increases the chance that this individual, when he reaches adolescence
  • 42:33 developments psychiatric diseases such as, for example, schizophrenia.
  • 42:38 Regardless of age, vitamin D insufficiency greatly enhances the appearance of depression.
  • 42:48 Depressive processes are favored or induced due to the presence of vitamin D deficiency,
  • 42:56 that is rarely taken into consideration by doctors today are treating people with depression.
  • 43:05 It is important to mention diabetes.
  • 43:10 Both the type 1, which is autoimmune, than that of type 2, which is that of maturity,
  • 43:19 both are highly favored by the deficiency of vitamin D.
  • 43:24 Insulin production is favored by vitamin D.
  • 43:29 Deficiency of vitamin D promotes the development of diabetes.
  • 43:35 In the field of diabetes, the effects of vitamin D deficiency are the subject of much research.
  • 43:52 These diseases are the most important to mention as regards their relationship with vitamin D.
  • 44:06 I have no information about it, but it does not mean it does not exist,
  • 44:14 that vitamin D may facilitate the removal of heavy metals from the body, I do not have this information.
  • 44:23 I have a strong belief that the onset of autoimmune diseases depends primarily on three factors:
  • 44:38 whether it be an individual who has inherited from the father or mother this predisposition,
  • 44:47 which concerns a partial resistenzia to the biological effects of vitamin D.
  • 44:53 It also depends on a second factor is the deficiency of vitamin D, due to the lack of sun exposure.
  • 45:03 And the third factor is the emotional factor.
  • 45:08 The latter would be the trigger that leads to the activation of autoimmune diseases,
  • 45:15 including multiple sclerosis,
  • 45:18 in persons with the two other factors that predispose to developing this disease.
  • 45:26 Only thing missing is the emotional factor triggering
  • 45:29 given by a life event high emotional stress. For example:
  • 45:35 a teenager or a teenager living her parents’ separation;
  • 45:40 an individual of 18, 19, 20 years of age who lives a break affective;
  • 45:49 a person of 30-35 years which sees the dissolution of his marriage;
  • 45:56 a great person who attends the unexpected death of his son.
  • 46:04 They are emotional traumas that eventually lead to the activation of the impact of autoimuni diseases, including multiple sclerosis.
  • 46:14 Given this experience, they have about 95% of patients with total control of the disease
  • 46:24 using high doses of vitamin D,
  • 46:27 it is not that we are excluding other factors that can contribute to the process,
  • 46:35 but if these factors are in fact contributing to the development of autoimmune diseases,
  • 46:42 their role is very minority of less importance physio-pathological effects of vitamin D
  • 46:50 or lack of imunomodulatori biological effects of vitamin D in our body.
  • 47:04 Many researchers say that a person with multiple sclerosis,
  • 47:10 having a neurological deficit that prevents her from walking freely,
  • 47:19 tends to remain indoors, inside,
  • 47:23 for this has less exposure to the sun and therefore has a lack of vitamin D.
  • 47:31 So the claim that vitamin D deficiency is a consequence of the disease and not the cause of the disease
  • 47:38 and this would be the issue.
  • 47:41 Well, this does not explain why, and already there are studies published in 1986,
  • 47:54 when evaluating in a patient, in the course of a few years, the amount of relapses,
  • 48:00 before and after being treated with vitamin D,
  • 48:09 these relapses decreased dramatically after treatment. The number of relapses, called “relapse”, have decreased drastically.
  • 48:19 This type of argument is excluding the crucial role of vitamin D, already well documented, as immunomodulator.
  • 48:31 In other words, vitamin D inhibits reactions in reference to all diseases autoinmuni
  • 48:38 and the reaction aberrant, non-physiological, called TH17.
  • 48:42 Vitamin D increases the amount of immunoregulatory lymphocytes.
  • 48:47 The level of vitamin D, how much more is high, the more will be the low activity of autoimmune disease; the lower level of vitamin D, the higher the activity of the autoimmune disease.
  • 49:06 If you consider all these factors together, you will only have one explanation:
  • 49:13 the lack of vitamin D leads to the autoimmune disease.
  • 49:18 Another factor that can be aggregated to this set, which is only explained to mean a lack of vitamin D,
  • 49:29 as a determinant of the occurrence of autoimmune disease or auxiliary
  • 49:33 is related to the difference of the equator,
  • 49:36 as we move away from the equator, the more you experience the presence of autoimmune diseases.
  • 49:43 If you look at a country that is well away from the equator, such as Norway, for example,
  • 49:53 we note that in the north of Norway the level of multiple sclerosis,
  • 50:00 contrary to the rule of the equator, you see fewer cases of autoimmune diseases such as multiple sclerosis,
  • 50:16 in relation to the south of Norway, where is located the city of Oslo.
  • 50:20 This too can be explained in relation to vitamin D,
  • 50:25 because in Northern Norway diet is basically composed of cosumo cold-water fish,
  • 50:36 which are rich in fatty fish, such as cod or salmon, which fats contain high amounts of vitamin D.
  • 50:44 So we can reverse the rule of the equator when there is the presence of vitamin D.
  • 50:58 The same thing occurs in Switzerland, in the Swiss Alps, in the city located about 2,000 meters above sea level,
  • 51:13 the amount of vitamin D in the blood is greater than that of the population in northern Switzerland
  • 51:24 and the north of Switzerland Winey more at sea level. So why is this happening?
  • 51:33 We can explain it by exposure to the sun.
  • 51:36 In municipalities located in elavate heights, to a position above the clouds, it is subject to greater sun exposure.
  • 51:45 Autoimmune diseases are not made easier because of the cold temperatures,
  • 51:51 because if it were otherwise, there would be more in the Swiss Alps cases.
  • 51:57 In the Swiss Alps there are fewer cases, because there is more sun exposure and as a result, more vitamin D.
  • 52:08 In the north of Switzerland there is less exposure to the sun
  • 52:13 and then smaller amounts of vitamin D circulating in the blood of the inhabitants, and therefore more autoimmune diseases.
  • 52:25 All of the epidemiology of autoimmune diseases, are made understandable by a single factor:
  • 52:33 deficiency of vitamin D.
  • 52:38 You can get to consider a single factor,
  • 52:41 single characteristic of epidemiological distribution of vitamin D and say, “No, but there is an alternative explanations have,
  • 52:55 people who are suffering from multiple sclerosis, those who have more severe forms of multiple sclerosis,
  • 53:04 have a higher vitamin D deficiency because they are more closed in the house. “
  • 53:07 It is an alternative explanation, but it does not explain all the other problems of the biological functions of vitamin D,
  • 53:18 all other epidemiological Characteristics of vitamin D. Epidemiological autoimmune diseases.
  • 53:41 The parathyroid hormone (PTH) is of extreme importance to us.
  • 53:49 Why? Because when administering vitamin D, vitamin D inhibits the production of parathyroid hormone.
  • 53:57 So, if I measure the parathyroid before starting to administer vitamin D and after 2 months,
  • 54:05 I use the lowering of parathormone (PTH what has dropped with the administration of vitamin D)
  • 54:14 I can use this as a parameter of the biological response to the effect of vitamin D.
  • 54:21 This is exactly the factor that we use to adjust the dose of vitamin D individually.
  • 54:30 If the vitamin D inhibits the production of PTH,
  • 54:33 I increase the level of vitamin D until the PTH reaches the value lower than normal.
  • 54:40 Do not suppress PTH, I only increase the vitamin D until the PTH comes close to the lower limit
  • 54:49 from the normal range of variation of PTH.
  • 54:54 From the production of this biological effect, I conclude that if vitamin D has achieved the maximum effect in the inhibition of PTH,
  • 55:05 must also have reached the maximum immunomodulatory effect.
  • 55:11 And, through this premise, we adjust the dose of vitamin D depending dell’abbassarsi of PTH.
  • 55:21 I can not suppress PTH, so as to make it undetectable, because if you suppress,
  • 55:31 I put the individual at risk.
  • 55:35 He’s taking a dose so high in vitamin D, which could subtract a large quatity of calcium from the bones.
  • 55:43 Increasing this excessive amount of calcium taken from the bones, and raising the concentration bleeds, it can impair renal function.
  • 55:53 Thus, the parathyroid hormone for us is a safety measure, a level of security.
  • 56:03 If I do not suppress PTH, I’m sure I’m not giving toxic doses of vitamin D.
  • 56:13 I can balance in relation to biological resistance to the effects of vitamin D on the grounds that that individual has genetic inheritance.
  • 56:28 I say this in other words.
  • 56:33 An individual may be in need of a dose of vitamin D, for example, 30,000 IU,
  • 56:42 to make sure that his parathormone reaches the value less than normal.
  • 56:46 Another individual may need to 100,000 IU to ensure that its PTH reaches this lower end of normal.
  • 56:55 Then, measure how much you lower the PTH, for us it is a way to adjust the dose of vitamin D,
  • 57:03 for the individual need of the patient.
  • 57:10 The level of PTH is the most readily available laboratory tests,
  • 57:18 that can give us an idea of ​​the strength of the person to the effects of vitamin D.
  • 57:28 There are other possibilities, other factors that we can measure.
  • 57:34 But the parathyroid hormone is made by all laboratories, it is not a great thing.
  • 57:39 Many doctors ask the dose of PTH.
  • 57:43 So, not a great test, a test is easily available at any place in the world.
  • 57:59 Somehow, I have already answered this question.
  • 58:06 A person who has a level of parathyroid near the upper limit of normal,
  • 58:130 this person probably has a level of vitamin D deficiency is very important.
  • 58:19 And they are getting calcium from the bones to maintain the calcium concentration of the blood,
  • 58:26 since it does not have enough vitamin D to absorb calcium from the intestine,
  • 58:32 from foods that transit in the intestine, which digests the intestine, due to the lack of vitamin D.
  • 58:38 Then, the person who has the parathormone near the upper limit of normal
  • 58:44 or above the upper limit of normal, that person has a very severe vitamin D deficiency.
  • 58:51 And this is something that varies so much for a person with an autoimmune disease,
  • 58:57 As for a healthy person.
  • 59:00 For example, if a person today has no autoimmune disease,
  • 59:05 This does not mean you can not have an autoimmune disease at any stage of its future.
  • 59:10 So, in terms of prevention,
  • 59:13 is very important that the person maintains its PTH level at least in the middle point,
  • 59:25 between the lower and upper value of the normal, through the administration of a realistic dose of vitamin D.
  • 59:33 Then, the same healthy person, taking vitamin D, 10,000 IU,
  • 59:39 probably (not definitely, but probably) this dose will be sufficient to maintain
  • 59:45 his parathormone inside the normal range of variation.
  • 59:49 Or close to the upper limit or above the upper limit.
  • 59:59 Yes, this is an important thing …
  • 60:03 The labs have different ranges of variation (range) to assess the normality of the parathyroid hormone.
  • 60:08 Then, a laboratory test that can tell he does, the way in which the measure parathyroid hormone,
  • 60:17 the normal level varies, for example, between 4 – 58 pg / ml.
  • 60:27 Another laboratory can say that for them the normal range is 12 to 65 pg / ml.
  • 60:41 So, the question on the level below 20
  • 60:46 is for people who use a lab that says the normal range of assessment is 12 to 65.
  • 60:51 It therefore must be of between 20 and 12.
  • 60:56 But a person who uses a second laboratory that says that the normal value is from 4 to 58,
  • 61:08 then I must remain between 10 and 4.
  • 61:11 The same thing that I explained earlier.
  • 61:13 I must be close to the lower limit of normal, but not below the lower limit of normal.
  • 61:19 I Doso vitamin D to achieve this effect.
  • 61:23 So, you do not need to be under 20.
  • 61:25 Below 20, or below 10, or between 12 and 20 or between 10 and 4, depends on what is the normal range
  • 61:35 that uses the laboratory as a reference.
  • 61:38 To which, depends on the laboratory.
  • 61:49 We have not yet assessed whether a weekly regimen may be better or worse
  • 61:59 a daily dose, or if a monthly administration may be better or worse
  • 62:08 of once per week.
  • 62:10 We have not done any study in this regard.
  • 62:14 We started from the assumption that only a good rule is that a person is exposed to the sun every day.
  • 62:23 So, if this is the norm, we try to adjust the dose according to the daily administration,
  • 62:31 and this is justified by the fact that you avoid large variations
  • 62:38 caused by doses very distanzati one another.
  • 62:42 So, when we administer on a daily basis,
  • 62:46 the variation of the concentration sanguingna you keep more regular, less swinging,
  • 62:55 and the magnitude of change will be minor.
  • 63:07 Who makes 10,000 units per day is taking a physiological dose,
  • 63:12 the same dose that would produce his skin when exposed to the sun for twenty minutes without sunscreen,
  • 63:21 wearing a short-sleeved shirt and shorts,
  • 63:24 in other words, leaving the arms and legs exposed to the sun, being a person of fair skin and young.
  • 63:29 So, this may not cause any problem to anyone because it is the amount that we produce normally.
  • 63:37 So, there is no necessity to go on a diet or any special hydration,
  • 63:41 in addition to that every individual should normally do to stay healthy.
  • 63:47 There is no need to take any precautions when taking 10,000 IU of vitamin D.
  • 63:53 My daughter takes 10,000 units of vitamin D per day for more than six years.
  • 63:59 There is no problem in taking 10,000 units of vitamin D per day,
  • 64:04 there is no need to take any precautionary measure.
  • 64:07 This, for sure, it is not a toxic dose,
  • 64:11 this dose is sold without a prescription in the United States without any problem.
  • 64:25 So, do not really know of any effect of vitamin D on the normal intestinal flora. If there is a publication in this regard is not to my knowledge.
  • 64:48 Because Vitamin D increases the power of reaction against the agents of disease,
  • 64:59 we can also expect that vitamin D reduces the presence of harmful bacteria in the gut. This hope.
  • 65:17 I have no information that says that vitamin D may alter harmful form in the digestive tract.
  • 65:26 It is possible that the lack of vitamin D deficiency is likely to affect the work of the digestive system,
  • 65:38 given that all our cells, including those of the digestive system, respond biologically to the effects of vitamin D.
  • 65:51 Alters its funzzioni in relation to the effects of vitamin D.
  • 65:58 The proper activity of the digestive tract can be stimulated with the correction of the deficiency of vitamin D.
  • 66:05 But, harmful effects caused by high doses of vitamin D (unless they are toxic, that is accompanied by a corresponding increase of calcium in the blood),
  • 66:19 harmful effects to the digestive system, there may be with the use of high doses of vitamin D, calibrated according to the laboratory tests.
  • 66:32 With regard to the vitamin D receptors,
  • 66:36 There are various diseases that are linked to genetic mutations in the vitamin D receptor,
  • 66:47 making these people resistant to vitamin D.
  • 66:54 The emergence of this resistance may be due to the fact that the individual in question has altered
  • 67:06 the enzyme that takes care of the activation of vitamin D, which are two hydroxylase.
  • 67:16 The individual may have an alteration of the first hydroxylase, the second hydroxylase,
  • 67:24 may have an alteration of the vitamin D receptor that is present in the cells, the objective of vitamin D.
  • 67:33 The idividuo may also have a genetic alteration of the protein that captures hereditary vitamin D and charge with it into the bloodstream.
  • 67:48 So, there are several genetic disorders that may explain the resistance of the individual assimilation of vitamin D.
  • 68:05 An individual also may need a lot more vitamin D to the fact of having an overweight for his height.
  • 68:16 Older people have then a lesser amount of vitamin D receptors in every single cell:
  • 68:27 decreases the concentration of vitamin D receptors in every single cell with increasing age.
  • 68:33 There are so many points that explain why in some cases a person sees increased its partial resistance to the effects of vitamin D.
  • 68:45 An individual may be suffering from two or three of these points that contribute to its resistance to the effects of vitamin D.
  • 68:55 For this, we use the final effect of this chain, which is the reduction in the levels of parathyroid hormone.
  • 69:06 It ‘ a way to avoid having to check what is actually the reason for the resistance.
  • 69:20 It does not matter if the reason is this, that is, or if there are multiple reasons for this resistance to concomitant vitamin D.
  • 69:28 Measuring the biological effect, which is the reduction of the levels of parathyroid hormone,
  • 69:32 we see the final effect of all these possible points of resistance to vitamin D,
  • 69:39 and is a way to optimize our work, and then to the best biological effect of vitamin D for that individual, regardless of the reason for which has a resistance.
  • 70:00 We simplify the whole measuring only a biological effect, which would be the reduction in the levels of parathyroid hormone.
  • 70:14 Yes, because when you produce vitamin D in the skin or ingested vitamin D,
  • 70:23 you are ingesting the inactive form of vitamin D, which is called colicalciferolo.
  • 70:29 This colicalciferolo undergoes the action of two enzymes, in a consecutive manner, to be transformed into the final shape,
  • 70:39 which is precisely the active form.
  • 70:41 Then, the colicalciferolo undergoes the action of an enzyme called 25-hydroxylase, which adds a chemical group
  • 70:50 called hydroxyl in position 25 of the molecule of colicalciferolo,
  • 70:56 colicalciferolo turning this into calcidiol-25-hydroxy-vitamin D,
  • 71:03 that is measured in the blood to detect whether or not the individual has deficiency.
  • 71:09 In turn this substance, 25-hydroxy-vitamin D or calcidiol, undergoes the action of a second hydroxylase, which adds
  • 71:21 another chemical group in position 1. Therefore, this enzyme, which is called 1-alpha-hydroxylase, can be genetically altered.
  • 71:32 Finally, it produces, through the second hydroxylase, the active form of vitamin D, 1,25-dihydroxy D3 call
  • 71:44 or calcitriol, which will then produce the final biological effect on the immune system and over all the cells in our body.
  • 71:55 Very well, these are dependent hydroxylase by vitamin B2,
  • 72:01 not directly, but indirectly,
  • 72:08 because in the step of hydroxylation of vitamin D, enzymes oxidize,
  • 72:19 and so that we can pick up a new molecule, hydroxylate another molecule, therefore,
  • 72:25 must be reduced, chemically called reduction process. And this reduction process requires the presence of vitamin B2.
  • 72:36 About 10-15% of the general population, the world in general,
  • 72:44 has great difficulty in absorbing vitamin B2. This is another genetic alteration that concerns IL10-15% of the population.
  • 72:55 In some regions of Italy who have had malaria endemic throughout the centuries, from 300 BC
  • 73:07 this percentage may be higher, it can reach 50% of the individuals concerned
  • 73:17 and these regions generally correspond to the peninsula of the Po, which is the region of Venice and another region on the west side of Italy …
  • 73:33 Another region that has had cases of malaria endemic in the course of several centuries, from 300 BC
  • 73:40 is Sardinia, where there have been cases of malaria endemic throughout the centuries.
  • 73:44 And, apparently, the people who had difficulty in absorbing vitamin B2 from food were resitenti to malaria,
  • 73:56 therefore, the children who had this genetic problem that they died of malaria in infancy,
  • 74:03 could pass into adulthood and passed on their genes to future generations,
  • 74:09 Unlike children who had this genetic alteration and were susceptible to malaria.
  • 74:17 So, most of the children who did not have this genetic alteration were dying of malaria in childhood
  • 74:25 and could not pass on their genes to future generations, reach adulthood and pass on their genes to the next generation.
  • 74:32 So, over the centuries, there was a natural selection in these regions of Italy are a lot more people
  • 74:40 with difficulty absorbing vitamin B2, riboflavin, compared to the rest of the world population,
  • 74:48 where it has about 10-15% of individuals with this difficulty absorbing riboflavin.
  • 74:59 In these regions of Italy, individuals descended from Italians, who also live in Brazil and are descended from Italian
  • 75:06 that come from those regions of Italy, have a greater chance of being carriers of this difficulty to absorb riboflavin.
  • 75:14 This (lack of B2) can contribute to resistance to vitamin D,
  • 75:17 because sometimes hydroxylase, in the absence of an adequate level of vitamin B2, will malfunction
  • 75:25 and will be another factor that will contribute to the resistance to vitamin D.
  • 75:32 So, for this reason, so that we should not be dosed vitamin B2 in all individuals,
  • 75:37 since it is not a test readily available in laboratories and the health care system does not cover these tests,
  • 75:49 not for the determination of vitamin B2, we administer vitamin B2, which is absolutely harmless,
  • 75:56 to all individuals, in a dose greater than that normally given, with the aim to cover the shortage …
  • 76:07 We measured the phosphorus because vitamin D is mobilizing calcium and phosphorus from the bone.
  • 76:15 And since we are using unpublished doses of vitamin D, this was also a suggestion
  • 76:23 Professor Michael Holick, so we dovumentare everything that’s going on.
  • 76:31 One of our concerns is that it is not altered phosphorus;
  • 76:40 that phosphorus levels are not altered.
  • 76:44 In fact, the dose we use, with these precautions, do not alter the levels of phosphorus.
  • 76:50 It’s just a precaution
  • 76:53 to have the certainty that the patients are well from the point of view workshop.
  • 76:59 All the laboratory parameters that can be altered for the use of high doses of vitamin D are measured
  • 77:07 and this is just one of them.
  • 77:10 This is the reason for which we measure the levels of phosphorus.
  • 77:22 Patients with kidney failure, for us it is a big problem
  • 77:27 giving them high doses of vitamin D.
  • 77:30 Because if I give a dose of vitamin D that causes excessive absorption of calcium, both of the bones of the intestine,
  • 77:40 I have to make sure that the kidneys expel him;
  • 77:44 However, if a person has the `kidney failure, I lose this certainty.
  • 77:49 So if a person has a kidney failure, this causes a lot more work,
  • 77:57 we have a lot more care than a person who has normal kidney function.
  • 78:04 Qusta is the only thing I can say `on` renal failure.
  • 78:08 There are diseases such as systemic lupus erythematosus, in which the immune system attacks the kidneys.
  • 78:16 We try to “stop” lupus before it causes renal injury.
  • 78:23 If the person already has renal lesions we have a lot more care.
  • 78:28 We start with a low dose of vitamin D for security that nothing will happen to the person.
  • 78:35 There is a need that the kidneys expel the excess calcium that is formed in the circulation
  • 78:43 and if the person has a kidney failure this becomes a problem.
  • 78:58 G6PD deficiency is one of the diseases which have increased in Italy as a result of endemic malaria.
  • 79:11 People with G6PD deficiency are resistant to malaria.
  • 79:19 It is the same type of natural selection that has happened with the deficiency of riboflavin.
  • 79:28 But I have no data to show me that vitamin D deficiency and G6PD are incompatible things,
  • 79:38 in the sense, that it can not give vitamin D to people who have deficiency of glucose-6-phosphate dehydrogenase,
  • 79:46 which is called G6PD.
  • 79:49 I see no incompatibility.
  • 80:03 I do not have this information, that vitamin D may help people with dystonia.
  • 80:10 For now I do not have, but I can do a search,
  • 80:16 because vitamin D is a substance that has many functions,
  • 80:26 all cells respond to vitamin D;
  • 80:31 the fact that I have no information on this, or the fact that there has been no published study on the relationship between vitamin D and dystonia,
  • 80:40 these things are not to indicate that vitamin D may not be beneficial to people with dystonia.
  • 80:45 But I do not own the `information available at this time.
  • 80:59 No, we have no patient with adrenoleukodystrophy, which is a metabolic disease.
  • 81:05 There is a direct relationship with vitamin D.
  • 81:09 Many people who have degenerative diseases of the nervous system, can potentially be favored
  • 81:17 a reasonable dosage of vitamin D.
  • 81:21 Surely, these people can not stay with vitamin D deficiency, because you sovvraporrebbero two factors:
  • 81:30 the genetic disorder, hereditary, metabolic, just one disease and, in addition, deficiency of vitamin D,
  • 81:37 which can accelerate the progression of the disease.
  • 81:40 Then, we suggest to people who have neurological or metabolic diseases that do not have a direct relationship with vitamin D,
  • 81:51 suggest that they should, most of the other people, to maintain normal levels of vitamin D.
  • 82:00 We do not recommend high doses of vitamin D, but only normal doses of 10,000 IU per day.
  • 82:10 These people have to worry, most of the other people, not to be deficient in vitamin D.
  • 82:25 For a patient who takes these anticoagulants with vitamin D?
  • 82:31 Basic there is no incompatibility with the vitamin D, to make the treatment with the vitamin D,
  • 82:39 or high dose of vitamin D, always observing precautions: diet and hydration.
  • 82:48 We have no information that would cause any problems with the `use of anticoagulants.
  • 82:56 A warning is important for people suffering from hyperthyroidism, or high levels of thyroid hormones,
  • 83:09 and that do not take drugs or do not follow treatment that maintains normal levels of thyroid hormones,
  • 83:22 these people can be very sensitive to the toxic effects of vitamin D.
  • 83:28 The thyroid hormone potentiates the effect of vitamin D in mobilizing calcium from the bones.
  • 83:37 These people are more sensitive to vitamin D, those with untreated hyperthyroidism, uncontrolled.
  • 83:46 This is a notice, we have had two cases of people who developed hyperthyroidism,
  • 83:55 which have become more sensitive to vitamin D than it usually occurs;
  • 84:03 the level of sensitivity of these people is higher than those that have the normal thyroid function.
  • 84:17 Yes, we say to patients who need to take antibiotics or anti-inflammatory drugs that are toxic to the kidneys,
  • 84:29 which should increase hydration. Do not just drink 2.5 liters of fluid,
  • 84:35 but an extra liter: 3.5 liters of fluid a day,
  • 84:39 Because when the drug passes to the kidneys, in this way is diluted and decreases the nephrotoxic effect, that is toxic to the kidneys.
  • 84:59 The person who assumes 10,000 units of vitamin D takes the same dose of vitamin D
  • 85:04 that a young man would if dressed in leather short-sleeved shirt and shorts,
  • 85:12 leaving arms and legs exposed to the sun, a young person and clear skin, without the use of sunscreen,
  • 85:22 would produce 10,000 IU of vitamin D, which can not be considered a toxic dose of vitamin D.
  • 85:32 And there is not no need to do laboratory tests or to be under medical supervision,
  • 85:38 for the simple fact that an adult is taking 10,000 units of vitamin D.
  • 85:43 This, however, is not valid when it comes to children;
  • 85:45 underweight children, this dose may be excessive.
  • 85:59 Yes, it is important that the symposium has both a logical and productive;
  • 86:04 which allows to get in touch with professionals willing to work with this protocol,
  • 86:16 using vitamin D in favor of the patients, in this case we have any interest.
  • 86:24 Unproductive would go to Italy only to do what you’re doing right now here,
  • 86:35 that is, only to orient the audience, because only be repeating the same things.
  • 86:40 The medical staff was concerned, other professionals who are interested in the results of this treatment,
  • 86:50 can ask technical questions that have not been made here today.
  • 87:04 So, in this situation it would be very produtivo a trip to Italy,
  • 87:11 for the amount of people that can have a benefit with this treatment,
  • 87:16 for young people who may be blind or paraplegic due to multiple sclerosis
  • 87:23 or who might suffer for a lifetime effects of a disease such as inflammation of the colon, and many others already mentioned.
  • 87:34 The presence of a professional in Italy and put into practice this treatment,
  • 87:42 would provide a benefit to people who live in Italy immeasurable.
  • 87:52 You have no idea of ​​the benefits that you might have.
  • 87:56 And he would have the same satisfaction, the same level of gratitude, immense, that we are receiving,
  • 88:03 keeping people above the impact (“high”) of multiple sclerosis and autoimmune diseases.
  • 88:08 We lose a patient when it reaches the expected result (“high”),
  • 88:14 but receive as reward a friend for life and this is something that is priceless.

The Coimbra protocol, a theraphy for autoimmune diseases

Explanation of the Coimbra protocol, a theraphy for autoimmune diseases this protocol can reverse auto immune issues. Over 2,500 MS sufferers are in remission from following this protocol.

IMPORTANT NOTE: the calcium intake through food must be low, but not too low, because this woud increase the PTH level, and the PTH could no more be used to measure the activity of vitamin D.

You may be able to mitigate calcium issues with high dose K2

The D3 effect

D3 is an amazing hormone. Since I started my health experiment it has caused various reactions from people most very encouraging happily supporting what I am doing. Because people know I’ve been constantly reading up on medical and health information, I am getting asked more and more about what they should take for this and that. My answer is always along the same lines I’m not a doctor you could try taking D3 but read about it first make sure you fully understand the dangers; I’m not convinced myself about all of the dangers but I know what they could be and am always on the lookout for them.

It has given me a greater appreciation of Doctors. We go to the Doctors expecting them to answer all our questions and come out with a prescription for some drug or other that will cure our issue. It must be sole destroying to be a Doctor in this day and age. That is why I was so encouraged to read the article that Jeff Knowles sent me about Dr Coimbra in Brazil. This Neurologist has pushed the boat out with his work using D3 to treat Neurological conditions, it’s so refreshing to read good news for a change. Unfortunately there are no followers of Dr Coimbra’s protocol in the UK where D3 is waiting for clinical trials, the general feeling in the UK is that D3 doesn’t work. It won’t work if the doses used are insufficient which they inevitably will be. Jeff Knowles’s work has shown how poor the knowledge is of D3 is in the medical community. The UK has not picked up on the fact that people with Neurological conditions do not metabolise D3 like other unaffected people might. Wake up to the global information out there, Now over 4,000 MS sufferers in remission worldwide surely that is the clinical trial that proves the effectiveness of D3. Many doctors around the world are coming on board with this to great effect, but sadly not in the UK

The Coimbra protocol explained


Jeff Knowles started getting pains in joints that were healing with his D3 experiment, so when I started on D3 I was expecting my left ankle to play up. I had sprained this ankle several times over the years, but the last x-ray I had showed that an earlier sprain wasn’t a sprain at all but I had chipped the bone and there was a small piece of the bone dislodged. So come the high doses of D3 I was waiting for my ankle to start hurting, well it did but only after I got my D3 doses up to 200,000 IU’s something I did just for a few days. I’d been on 100,000 for over a month before I upped the dose.

I am definitely not any expert but what I am doing is working for me and I highly recommend it, but not without reading and gaining an understanding about the undertaking. Don’t bother with any experiment with your health if you’re not prepared to embrace it totally 200%. If you have MS like me:-

  • You must alter your diet.
  • You must be prepared to be more active and embrace building up your fitness and exercise.
  • If you are in a family environment and not living alone. You must get support from your family they may also need to embrace your dietary changes as well. This will get very difficult if you are surrounded by people on a different diet than that you are on.
  • You must drink 3 litres or more of water a day or more herbal teas can be counted towards the 3 litres total as well.

Don’t rush expecting miracle improvements right away a disease like MS may have taken say 20 – 40 years or more to form there is no magic pill that will resolve your symptoms overnight. I gave myself 2 years at the start of this to see if it had any impact, but it’s now only 15 months in and I know I’m now committed for life. The improvements were obvious within about 4 months nothing major but enough to convince me that I’m on the right path.

Before you start get your D3 levels tested. If your doctor won’t do this you can do a home test in the UK the following site offers more information about what’s involved, but it’s just a spot of blood on a slide, nothing too difficult.

Blood Spot Test Kit Order Line

Tel: +44 (0)121 507 4278

Monday – Friday 09.00 – 17.00 UK time

Actually it’s kind of criminal that doctors don’t get a D3 test done for all of their patients on a regular basis, especially if you live in the Northern hemisphere.

Before you start I suggest you have a clear understanding of the symptoms to look out for if you may encounter a problems with your health experiment:-

Although most people take vitamin D supplements without any problems, it’s possible to take too much. This is called vitamin D toxicity. When your 25(OH)D levels are too high, this can cause high levels of calcium to develop in your blood. High blood calcium is a condition called hypercalcemia. Now if you have an auto immune disease like me it is now known that our ability to process D3 is compromised. Before you start on high doses you will probably get results of a D3 blood test coming back as deficient then after high doses excessive. You should just be concerned with ensuring you have none of the symptoms of D3 toxicity. I had no symptoms when the lab came back to me telling me I was 1,000 times over the recommended limit that was a few months ago and I still have no symptoms, and all my doctors checks gave me showed no issues though I obviously had a thyroid issue which I am reversing with selinium, ashwagandha, magnesium and tumeric current NHS test are inadequate for thyroid they are checking for Throyd hormone levels in your brain not your cells, by the time your brain is affected you are most probably very poorly. How did I know? Well I lost the hair on the end of my eye brows and lower lashes. Not now if i was dealing with a functional medicine practitioner the would have looked at me as a whole entity and noticed this.

I also found a Vitamin B issue my nails started to get ridges a Niocin deficiency.

The symptoms of hypercalcemia include:

  • Feeling sick or being sick
  • Poor appetite or loss of appetite
  • Feeling very thirsty – unlikely if you are following the recommendation of drinking 3 litres of water a day.
  • passing urine often – this one is difficult to judge as with MS you may already have this as an issue before starting any supplements but think have things changed. Drinking the 3 litre of waters per day is required so again it’s impossible to judge this one properly! I recommend if you can drinking more than 3 litres.
  • Constipation or diarrhoea – Well this should be easy if like me you have changed your diet to one high in fibre, things in this area should have dramatically improved so changes will be noticeable, but you still should not have any abnormal bowel movements.
  • abdominal pain
  • Muscle weakness or pain – Another one difficult to judge so again think have things changed. I found occasional aches, but only twinges really and once I built up my activity they soon disappeared.
  • bone pain
  • Feeling confused -Another one difficult to judge so again think have things changed? I was suffering from brain fog before D3 but not since or at least I’m not noticing it any more.
  • Feeling tired – Again think have things changed?

On the results of the 25(OH)D test you’ll have the results ranked as to where you are within the recommended standard. The standard quoted is extremely low. People with MS metabolise D3 differently I was 1,000 times over the recommended limit at one time with no adverse affects  (the Lab panicked and phoned me) but don’t panic too much about these results get advice from your doctor but be warned they will know less than you on this journey once you start reading up.

Holick MF. Calcium and Vitamin D. Diagnostics and Therapeutics. Clin Lab Med. 2000 Sep;20(3):569-90)

Most people in the UK will be deficient. I was in the normal range when I started but I had been taking 5,000 IU’s daily for 10 years prior to starting this journey, that dose hadn’t made any difference to me, also I’d been on JuicePlus for 6 months which is a product high in D3 so my levels would have been distorted before the start of my D3 experiment. The way I judged it was based on Jeoff’s book he noticed pain from joint remodelling so I based my doses on whether I noticed any pain in my ankle where I had a chipped bone. I built up to 100,000 D3 tablets for a month after 6 months and I still noticed no ankle pain. I went onto 200,000 for a few days and instantly noticed some pain. I backed off to the amount recommended by Dr Coimbra based on my weight so have settled to 60,000 a day with my main meal. I am still getting a small amount of pain in my ankle so I think the remodelling has started but will probably be slower as I have lowered the dose. I’ll probably give it about a month and if no different will up the does again for a few days.

It’s all about listening to your body if things are changing are they changing for the better? The one test that is vital is your blood calcium level if that is normal and you feel normal then you’re doing great, If anything is changing for the worse stop the D3 and rethink what you are doing. Have you adjusted your diet, are you’re taking sufficient K2 and is it the MK4 or MK7 version, some people taking the MK4 version got heart palpitations, make the switch as per Jeff’s book.


Skip to toolbar